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Diphtheria Antitoxin

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Diphtheria Antitoxin

Diphtheria Antitoxin
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Approx. Rs 950 / Piece
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Product Details:
Minimum Order Quantity50 Piece
Injection SiteIntramuscular
Storing Temperature2 to 8 deg C

Other Details:
  • B.No.: 04AD16004
  • Mfg: 09/16
  • Exp: 08/18
  • Mfg Lic No.: 01/MN/AP/03/Sera/G
  • Include all taxes

What Is Diphtheria:
  • Diphtheria is a bacterial disease caused by Corynebacterium diphtheriae.
  • The infection commonly affects the throat and may lead to obstruction of the airways and death.
  • Exotoxin-induced damage occurs to organs such as the heart.
  • Nasal diphtheria may be mild, and chronic carriage of the organism frequently occurs; asymptomatic infections are common.
  • Transmission is from person to person, through droplets and close physical contact, and is increased in overcrowded and poor socioeconomic conditions.
  • A cutaneous form of diphtheria is common in tropical countries and may be important in transmission of the infection.

  • Diphtheria affects people of all ages, but most often it strikes unimmunized children.
  • In temperate climates, diphtheria tends to occur during the colder months.
  • In 2000, 30000 cases and 3000 deaths of diphtheria were reported worldwide.

  • The symptoms of diphtheria usually begin two to seven days after infection.
  • Symptoms of diphtheria include fever, chills, fatigue, bluish skin coloration, sore throat, hoarseness, cough, headache, difficulty swallowing, painful swallowing, difficulty breathing, rapid breathing, foul-smelling bloodstained nasal discharge and lymphadenopathy.
  • Symptoms can also include cardiac arrhythmias, myocarditis, and cranial and peripheral nerve palsies.

  • Patients with severe cases will be put in a hospitalintensive care unit and be given a diphtheria antitoxin.
  • Diphtheria antitoxin is hyperimmune serum Produced in horses.
  • Plasma obtained from healthy horses with diphtheria toxin is enzyme refined, purified and concentrated.
  • The antitoxin has the specific capacity of neutralizing the toxin secreted by Corynebacterium diphdheriae, the causative organism of Diphtheria.
  • Antitoxin will only neutralize circulating toxin that is not yet bound to tissue, thus prompt administration is critical.
  • Delayed administration increases the risk oflate effects such as myocarditis and neuritis.
  • Before antitoxin is administered, the patient should be tested for sensitivity to horse serum and if necessary,desensitized.
  • The dose of antitoxin to be administered depends upon the site and extent of the diphtheritic membrane, the degree of toxicity and the duration of illness.
  • Prevention: Toxoid as DTP, DT or Td - at least three primary doses given.
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